Research in the lab involves generating and analyzing large-scale cancer genomics data to study carcinogenesis and tumor progression at a molecular level, and to identify molecules that may have clinical applications for better diagnosis, prognosis or therapeutic use.
We are employing multiple technologies to generate global landscapes including genome, epigenome and transcriptome profiles of tumor specimens, and are applying diverse and integrative analytical approaches to these datasets in order to identify cancer-driving aberrations. Most of our projects utilize next-generation-sequencing (NGS) and include a computational data analysis component. We also undertake experimental approaches to functionally characterize promising candidate molecules identified from our genome-scale studies.
Our research is supported by extensive collaboration with other groups at McGill University, elsewhere in Canada and internationally.
Our lab is located in the McGill University and Genome Québec Innovation Centre. We are also affiliated with the Department of Human Genetics and Goodman Cancer Research Centre at McGill University.